The purification of formol diphtheria toxoid by multi-membrane electro-decantation.

Preparation and Evaluation of Diphtheria Toxoid-Containing Microspheres

Preparation of chitosan (CS) microspheres as a novel drug delivery vehicle for intranasal immunization using high, medium and low CS molecular weight (MW) was investigated in this study. Diphtheria toxoid (DT) was used as a model antigen. The emulsion-solidification method was adopted for microencapsulation of DT.  In the first step, following the purification of semi-crude DT by the ion-exchan...

Preparation and Evaluation of Diphtheria Toxoid-Containing Microspheres

Preparation of chitosan (CS) microspheres as a novel drug delivery vehicle for intranasal immunization using high, medium and low CS molecular weight (MW) was investigated in this study. Diphtheria toxoid (DT) was used as a model antigen. The emulsion-solidification method was adopted for microencapsulation of DT.  In the first step, following the purification of semi-crude DT by the ion-exchan...

Study on Diphtheria Toxin Purification: A New Approach to Prepare Toxoid.

Clxxxiii. Purification of Diphtheria Toxoid. by Peter Joseph Moloney and Morton

METHODS' for the purification of diphtheria toxoid may be divided into two classes; those which give a moderate degree of purification and a high yield, and those which give a high degree of purification and a yield which varies within wide limits. Among the latter is the method first applied to toxin by Glenny and Walpole [1915] and later modified by Watson and Wallace [1924] for toxin and by ...

Preparation and evaluation of chitosan nanoparticles containing Diphtheria toxoid as new carriers for nasal vaccine delivery in mice

 The aim of me present work was to investigate rhe potential utility of nanoparticles made of chitosan (CS) and also CS chemically modified with polyethylene glycol (CS-PEG) as new vehicles for improving na^al vaccine delivery. For mis purpose, diphtheria toxoid (DT) was chosen as a model antigen. DT was entrapped within nanoparticles made of CS of different molecular weight, and also made of C...